Summary:
A University of Paris research study proves that in brain tissue (neuron cell) cultures, the production of the brain neurotransmitters, such as dopamine, can be increased by adding NADH to the culture medium.

The study's results showed that adding NADH yields a six-fold increase in the production of the neurotransmitter dopamine. It was also found coenzyme NADH stimulates the production of many different brain neurotransmitters, including dopamine, norepinephrine or noradrenaline, and serotonin.

Benefits of dopamine production:
NADH stimulates dopamine production. Medical science has proven that increased dopamine production has a positive effect on the following brain functions: thinking, cognitive functions (like memory & decision making), sex drive, mood, drive, strength, coordination, movement, mobility and much more.

Medical science has proven dopamine has a positive impact on growth hormone secretion. Growth hormone secretion is regarded as the key factor for the regeneration of cells and tissue. Increased dopamine production enhances the body's ability to repair or replace damage and wounded cells.

Dopamine has been proven to reduce prolactin secretion, which is the cause of appetite. The higher the dopamine levels in the blood, the lower the appetite. It is believed that higher or normalized dopamine blood levels reduces "binge" eating.

Parkinsonian related neurotransmitters:
In a double blind placebo controlled study performed at a German university hospital, Parkinsonian patients were treated with NADH or a placebo. The patients receiving NADH showed elevated levels of L-dopa and dopamine in the blood. Medical science has proven that Parkinson's disease occurs when the brain cells that produce dopamine die. All Parkinsonian patients in this German study who were taking NADH improved in their condition. (See the Parkinson's disease section for more information about NADH and Parkinson's disease.)

Definition of neurotransmitter:
A neurotransmitter is the chemical that transmits information across the junction (synapse) that separates one nerve cell (neuron) from another nerve cell or a muscle.

Neurotransmitters are stored in the end of the nerve cell's bulbous (also called axon). When an electrical impulse traveling along the nerve reaches the axon, a neurotransmitter is released. It travels across the synapse, either prompting or inhibiting continued impulses. There are more than 300 known neurotransmitters.

More types of neurotransmitters:
Other university studies performed in France found that NADH stimulates not only the increase production of dopamine, but also norepinephrine in certain brain areas, by more than 40%.

Norepinephrine, also known as noradrenaline mediates chemical communication in the sympathetic nervous system. The sympathetic nervous system functions in response to short-term stress and anxiety (the fight or flight response). Medical science has proven that norepinephrine mediates the heart rate, blood pressure, the rate of glycogen (glucose) conversion for energy, as well as and other physical benefits.

For our readers, who want it in scientific terms Dopamine's protection against brain damage:
In neuron cell cultures, dopamine production can be increased by adding NADH to the culture medium. In a dose dependent manner, NADH yields a six-fold increase production of dopamine. Furthermore, NADH stimulates tyrosine hydroxylase (TH), the key enzyme for the production of dopamine in a dosage dependent manner of up to 70%.

The neurotransmitter dopamine undergoes what is called auto-oxidation. This process forms cytotoxic agents that may damage very sensitive areas in the basal brain. Research has found auto-oxidation occurs significantly more often in older individuals. A dopamine auto-oxidation inhibiting substance is useful in reducing damage to certain areas within the brain, by retarding cell death and tissue degeneration.

An elevated NADH level results in a significant elevation of pyridine dinucleotide levels in the brain. The brain has an active uptake mechanism for the accumulation of nicotinamide through the choroid plexus, indicating this is an important functional role for brain metabolism and oxidative defense. Taken all these factors into account one can conclude that NADH has a protective affect on the brain.

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